个人简介：
张凯华，女，山东莒南人，理学博士，硕士生导师，bob在线登录准聘副教授。
教育/工作经历：
2024年1月-至今 bob在线登录 准聘副教授
2021年03月-2023年12月 bob在线登录 讲师
2018.11 - 2020.12 美国 约翰斯·霍普金斯大学 医学院 博士联合培养
2016.09 - 2020.12 厦门大学 电子科学与技术学院 无线电物理 博士
2013.09 - 2016.07 华东师范大学 物理与电子科学学院 无线电物理 硕士
研究方向：
磁共振成像与医学应用（儿童青少年脑发育疾病、产后抑郁、痴呆等），核磁共振理论与方法
硕士招生方向
基础心理学：多模态磁共振成像研究焦虑抑郁、痴呆、帕金森等心理及脑机制
心理健康教育：心理健康问题预测/干预/治疗
主持/参与课题：
(1) 国家自然科学基金委员会青年项目，基于多模态分层fMRI研究主观认知下降患者内嗅皮层编码和提取的异常神经机制，2023-01至2025-12，30万元，主持；
(2) 山东省自然科学基金委员会青年项目，产后抑郁患者情绪加工障碍的神经机制研究，2023-01至2025-12，15万元，主持；
(3) 国家自然科学基金委员会，面上项目，高保真超快速时空编码核磁共振成像新技术及其应用，2018-01至2021-12，66万元，参与；
(4) 国家自然科学基金委员会，面上项目，原发性单症状遗尿症儿童相关认知功能障碍的fMRI研究，2016-01至2019-12，58万元，参与；
发表论文：
1. Kaihua Zhang, Liuyi Chen, Yinghao Li, Adrian G Paez, Xinyuan Miao, Di Cao, Chunming Gu, James J Pekar, Peter C M van Zijl, Jun Hua, Arnold Bakker. Differential laminar activation dissociates encoding and retrieval in the human medial and lateral entorhinal cortex. Journal of Neuroscience. 2023 Mar 21:JN-RM-1488-22.(IF=6.709, 神经科学一区经典top期刊)
2. Chao Zhang#, Kaihua Zhang#, Xin Hu, Xianyun Cai, Yufan Chen, Fei Gao, Guangbin Wang, Regional GABA levels modulate abnormal resting-state network functional connectivity and cognitive impairment in multiple sclerosis, Cerebral Cortex, 2024, 34(2), bhad535.(共同一作，IF=3.7, 神经科学领域经典 top 期刊)
3. Kaihua Zhang; Xiaoyu Du; Xianling Liu; Wei Su; Zhenhua Sun; Mengxing Wang; Xiaoxia Du ; Gender differences in brain response to infant emotional faces, BMC Neuroscience, 2022, 23(1): 23(1)-79. (IF=3.264)
4. Kaihua Zhang, et al., Xiaoxia Du*, Marc H. Bornstein* . Brain Responses to Emotional Infant Faces in New Mothers and Nulliparous Women. [J]. 2020, 10(1):9560. Scientific Reports. (IF=4.996)
5. Kaihua Zhang, et al., Xiaoxia Du*, Zhong Chen*. Brain structural plasticity associated with emotional processing in postpartum women: A longitudinal voxel-based morphometry study. [J]. Neurodegenerative Diseases, 2019, 19(5-6): 192-203. (IF=3.417)
6. Kaihua Zhang, et al., Xiaoxia Du*, Zhong Chen*. Dynamic Alterations in Spontaneous Brain Activity in Mothers: A Resting-State Functional Magnetic Resonance Imaging Study. [J]. Neuroscience Bulletin, 2019, 35(4):766-770. (IF=5.271)
7. Kaihua Zhang, et al., Xiaoxia Dua,* Neural activation of human imitation based on performance feedback: an fMRI study. [J]. Neuroscience Letters, 2016, 629(202. (IF=3.197)
8. Kaihua Zhang, et al., Xiaoxia Du*. Task positive and default mode networks during a working memory in children with primary monosymptomatic nocturnal enuresis and healthy controls. [J]. Pediatric Research, 2015, 78(4): 422-9. (IF=3.953，儿科研究)
9. 张凯华、林嘉玉、宿薇、高璎莉、et al. 杜小霞*. 产后女性脑镜像同伦功能连接改变的静息态fMRI研究 [J]. 磁共振成像, 2024.03
10. Kun Zeng, Hong Zheng, Congbo Cai, Kaihua Zhang, Zhong Chen*. Simultaneous single- and multi-contrast super-resolution for brain MRI images based on a convolutional neural network. [J]. Computers in Biology and Medicine, 2018, 1;99:133-141. (IF=6.698)
11. Mengxing Wang, Kaihua Zhang, et al., Xiaoxia Du,*. Abnormal Neural Responses to Emotional Stimuli but Not Go/NoGo and Stroop Tasks in Adults with a History of Childhood Nocturnal Enuresis. [J]. Plos One, 2015, 10(11): e0142957. (IF=3.752)
12. Du Lei, Jun Ma, Jilei Zhang, Mengxing Wang, Kaihua Zhang, Fuqin Chen, et al. Xiaoxia Du*. Connectome-Scale Assessments of Functional Connectivity in Children with Primary Monosymptomatic Nocturnal Enuresis. [J]. Biomed Research International, 2015, 2015(19): 1-8. (IF=3.246)
13. Bornstein M. H., Putnick D. L., Rigo P., et al., Kaihua Zhang, Cote L. R., De Pisapia N., Venuti P. Neurobiology of culturally common maternal responses to infant cry [J]. PNAS, 2017, 114(45): E9465-E73. (IF=12.779)
14. 张慧, 王梦星, 张凯华, et al. 杜小霞* .儿童青少年反应抑制能力的发展:基于 Go/NoGo 任务的功能 MRI 研究 [J]. 磁共振成像, 2015,11): 860-5.
15. 王梦星，雷都，张慧，张记磊，张凯华，马俊，杜小霞*.注意缺陷型和混合型 ADHD 儿童在 GO/Nogo 任 务中的脑功能 MRI. [J]. 中国医学影像技术, 2016, 32(5): 678-82.
会议论文：
1. Yang Zhang, Wei Su, Xiaoyu Du, et al., and Kaihua Zhang*. Altered white matter diffusion properties and gray matter volume in classical trigeminal neuralgia. 2023 ISMRM & ISMRT Annual Meeting & Exhibition, Toronto, Canada.
2. Kaihua Zhang, Xiaoyu Du, Xianling Liu, et al.. Gender differences in brain response to infant emotional faces. 2023 ISMRM & ISMRT Annual Meeting & Exhibition, Toronto, Canada.
3. Jiayu Lin, Wei Su, Xiaoyu Du, et al., and Kaihua Zhang*. Maternal neural and behavioral sensitivity to baby emotional sounds. 2023 ISMRM & ISMRT Annual Meeting & Exhibition, Toronto, Canada.
4. Kaihua Zhang, et al., Peter C. M. van Zijl*, Arnold Bakker, Jun Hua* Layer specific T2-prepared BOLD fMRI in the entorhinal cortex at 7T. 80048694 - ICP Network Symposium: Physiological and Functional MRI of the Brain: Emerging Techniques and Clinical Applications, 2019.
5. Kaihua Zhang, Mengxing Wang, Jilei Zhang, Haifeng Lu, Zhong Chen*, Xiaoxia Du* Dynamic development of spontaneous neuronal activity in postpartum women: A longitudinal resting-state functional MRI study. Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.
6. Kaihua Zhang, Mengxing Wang, Xueyun Su, Jilei Zhang, Junyao Xie, Haifeng Lu, Zhong Chen*, Xiaoxia Du* Brain structural plasticity associated with emotional processing in postpartum women: A longitudinal voxel-based morphometry study. Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.
7. Kaihua Zhang, Hui Wang, Mengxing Wang, Jilei Zhang, Hui Zhang, Xiaoxia Du*. Neural substrates of human imitation based on performance feedback: an fMRI study. 15th Conference for the International Society of Magnetic Resonance, Shanghai, China, 2015.
8. Kaihua Zhang，Mengxing Wang，Jilei Zhang，Haifeng Lu，Xiaoxia Du*，Zhong Chen*. Neural Response to Infants’ Emotional Stimuli in Chinese New Mothers: an fMRI Study. The 17th Annual Meeting of Chinese Society of Magnetic Resonance in Medical (CSMRM) of Chinese Society of Radiology (CSR) joint with 2017 Overseas Chinese Society of Magnetic Resonance in Medicine (OCSMRM) Annual Meeting & The 17th Annual Meeting of Radiologic Society of Shanxi Province, 2017.06.
9. Kaihua Zhang, xueyun Su, Mengxing Wang, et al., Zhong Chen*, Xiaoxia Du*. Brain Structural Plasticity in Chinese New Mothers: A Voxel-based Morphometry Study. Chinese congress of radiology 2017, the 7th oriental congress of radiology, 2017.10.
10. Mengxing Wang, Jing Zhang, Guohua Shen, Jilei Zhang, Kaihua Zhang, Guang Yang, et al. Xiaoxia Du*. Resting-state functional MRI for evaluation of brain development from childhood to young adulthood. Proc. Intl. Soc. Mag. Reson. Med. 2014; 22: 5479.
11. Jilei Zhang, Yi Qiao, Mengxing, Kaihua Zhang, et al., Altered spontaneous brain activity in male adolescents with violent behavior: a resting-state functional MRI study. Conference: the 19th International Society of Magnetic Resonance, August 2015
12. Jilei Zhang, Kaihua Zhang, Mengxiang Wang, Zhengyu Du, Xiaoxia Du*. Measurement of fat distribution in idellus by magnetic resonance imaging. The 18th session of the national spectroscopy academic year, F, 2014 [C].
指导学生获奖：
(1) 2023年指导项目“探寻原发性遗尿症儿童风险筛查的影像学指标——基于多模态MRI与人工智能”获大学生创新创业计划训练国家级立项；
(2) 2023年指导项目“谁动了我的奶酪？——主观认知下降患者内嗅-海马记忆环路的编码和提取异常神经机制及表征模式的功能磁共振成像研究”获大学生创新创业计划训练国家级立项；
(3) 2023年指导bob在线登录2023年度本科生科研基金立项“产后抑郁女性异常神经机制研究——基于多模态 MRI 技术”（批号：BKJJ2023086）
(4) 指导本科生发表3篇国际顶级医学磁共振学术会议ISMRM论文，其中2篇受邀2023年6月份前往加拿大多伦多作口头报告。
联系方式
电子邮箱：zkh9013@126.com
通讯地址：山东省济南市长清区大学路1号bob在线登录406，邮编250358